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COMP
| Detection range: | 0.312-20ng/mL |
| Sensitivity: | 0.120ng/mL |
| Type: | Traditional COMP ELISA kit |
| Synonyms: | MED; EDM1; EPD1; PSACH; THBS5; TSP-5; Pseudoachondroplasia,Epiphyseal Dysplasia 1,Multiple; Thrombospondin 5 |
| Species: | Bovine |
| Sample type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| UniProt ID: | P35445 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable protein domain specific binding activity and signaling receptor binding activity. Involved in several processes, including estrous cycle; regulation of cell morphogenesis; and regulation of synaptic signaling by nitric oxide. Acts upstream of or within Wnt signaling pathway, planar cell polarity pathway. Located in extracellular space. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Biomarker of colon cancer. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A).
