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OASL
| Detection range: | 15.6-1000pg/mL |
| Sensitivity: | 6.2pg/mL |
| Type: | Traditional OASL ELISA kit |
| Synonyms: | TRIP14; p59OASL; 59 kDa 2-5-oligoadenylate synthase-like protein; Thyroid receptor-interacting protein 14 |
| Species: | Human |
| Sample type: | serum, plasma, cell lysates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 8638 |
| UniProt ID: | Q15646 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
