| Detection range: | 31.2-2000pg/mL |
| Sensitivity: | 14.3pg/mL |
| Type: | Traditional CTSD ELISA kit |
| Synonyms: | CPSD; CLN10; Lysosomal Aspartyl Protease; Ceroid-Lipofuscinosis,Neuronal 10 |
| Species: | Mouse |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 13033 |
| UniProt ID: | P18242 |
| Component: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable calcitonin receptor binding activity; hormone activity; and identical protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; cellular response to tumor necrosis factor; and vasodilation. Located in axon; extracellular space; and neuronal cell body. Is active in hippocampal mossy fiber to CA3 synapse and neuronal dense core vesicle. Used to study acute necrotizing pancreatitis; ischemia; and stomach disease. Biomarker of middle cerebral artery infarction; migraine; prediabetes syndrome; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to human CALCA (calcitonin related polypeptide alpha).
