serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
14854
UniProt ID:
P51855
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables several functions, including beta-catenin binding activity; dynein complex binding activity; and tau-protein kinase activity. Involved in several processes, including apoptotic signaling pathway; positive regulation of organelle organization; and regulation of macromolecule biosynthetic process. Acts upstream of with a positive effect on autosome genomic imprinting. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus; positive regulation of protein metabolic process; and regulation of neuron projection development. Located in several cellular components, including dendritic shaft; growth cone; and neuronal cell body. Part of Wnt signalosome; beta-catenin destruction complex; and ribonucleoprotein complex. Is active in glutamatergic synapse; meiotic spindle; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; immune system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; bipolar disorder; oral squamous cell carcinoma; and schizophrenia. Orthologous to human GSK3B (glycogen synthase kinase 3 beta).
