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Lmna
| Detection range: | 0.312-20ng/mL |
| Sensitivity: | 0.115ng/mL |
| Type: | Traditional LMNA ELISA kit |
| Synonyms: | CDCD1; CMD1A; CMT2B1; EMD2; FPL; FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1; Cardiomyopathy Dilated 1A; Limb Girdle Muscular Dystrophy 1B; Progeria 1 |
| Species: | Mouse |
| Sample type: | tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 16905 |
| UniProt ID: | P48678 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Predicted to enable sterol ester esterase activity. Acts upstream of or within several processes, including ATP metabolic process; hematopoietic or lymphoid organ development; and hemopoiesis. Is active in lysosome. Is expressed in several structures, including adrenal cortex zone; alimentary system; brain; hemolymphoid system; and metanephros. Used to study Wolman disease and lysosomal acid lipase deficiency. Human ortholog(s) of this gene implicated in Wolman disease and cholesterol ester storage disease. Orthologous to human LIPA (lipase A, lysosomal acid type).
