CD156-C; CD156c; MADM; Kuz; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloprotease
Species:
Rat
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
29650
UniProt ID:
Q10743
Component:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables metalloendopeptidase activity. Involved in several processes, including amyloid-beta formation; regulation of dendritic spine morphogenesis; and response to antineoplastic agent. Located in several cellular components, including postsynaptic membrane; synaptic vesicle; and trans-Golgi network. Is active in glutamatergic synapse and postsynapse. Biomarker of several diseases, including Alzheimer's disease; cataract; status epilepticus; thoracic aortic aneurysm; and traumatic brain injury. Human ortholog(s) of this gene implicated in Alzheimer's disease 18 and reticulate acropigmentation of Kitamura. Orthologous to human ADAM10 (ADAM metallopeptidase domain 10).
