BGLAP; OT; BGP; Bone Gla Protein; Bone Gamma-Carboxyglutamate Protein; Gamma-carboxyglutamic acid-containing protein
Species:
Rat
Sample type:
serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
25295
UniProt ID:
P04640
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
A structural constituent of bone. Involved in several processes, including cellular response to vitamin D; cellular response to zinc ion starvation; and osteoblast development. Located in several cellular components, including dendrite; extracellular space; and perikaryon. Used to study congenital hypothyroidism and osteoporosis. Biomarker of autosomal dominant hypocalcemia; end stage renal disease; and polycystic kidney disease. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein).
