Sidebar
Defb1
| Detection range: | 0.781-50ng/mL |
| Sensitivity: | 0.27ng/mL |
| Type: | Traditional DEFβ1 ELISA kit |
| Synonyms: | B-DF1; DEFB1; BD1; DEF-B1; DEFB101; HBD1 |
| Species: | Rat |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 83687 |
| UniProt ID: | O89117 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables several functions, including amine binding activity; enzyme binding activity; and sodium:chloride symporter activity. Involved in several processes, including dopamine transport; response to cAMP; and response to ethanol. Located in neuron projection and plasma membrane. Is active in dopaminergic synapse; postsynaptic membrane; and presynaptic membrane. Biomarker of Parkinsonism; heroin dependence; high grade glioma; hyperprolactinemia; and hypertension. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; classic dopamine transporter deficiency syndrome; mild cognitive impairment; nicotine dependence; and obesity. Orthologous to human SLC6A3 (solute carrier family 6 member 3).
