serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
54250
UniProt ID:
P13109
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables H3K9me3 modified histone binding activity and fibroblast growth factor receptor binding activity. Involved in several processes, including behavioral response to ethanol; positive regulation of cell population proliferation; and regulation of intracellular signal transduction. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in extracellular space. Used to study alcohol use disorder and pulmonary hypertension. Biomarker of several diseases, including cocaine abuse; decubitus ulcer; hypertension; middle cerebral artery infarction; and retinal vascular disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2).
