| Detection range: | 15.6-1000pg/mL |
| Sensitivity: | 4.63pg/mL |
| Type: | Traditional GT ELISA kit |
| Synonyms: | GAST; GAS; Gastrin component I; Big gastrin; Gastrin component II; Gastrin component III |
| Species: | Rat |
| Sample type: | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Experimental method: | Competitive inhibition |
| Shelf life: | 12 months |
| Gene ID: | 25320 |
| UniProt ID: | P04563 |
| Components: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables several functions, including glutathione binding activity; glutathione-disulfide reductase (NADPH) activity; and nucleotide binding activity. Involved in several processes, including response to iron(III) ion; response to ischemia; and response to vitamin A. Predicted to be located in external side of plasma membrane. Predicted to be active in cytosol and mitochondrion. Used to study cataract and transient cerebral ischemia. Biomarker of several diseases, including acute kidney failure (multiple); artery disease (multiple); hemorrhagic cystitis; myoglobinuria; and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase).
