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Glud1
| Detection range: | 1.56-100ng/mL |
| Sensitivity: | 0.63ng/mL |
| Type: | Traditional GDH ELISA kit |
| Synonyms: | GLUD1; Glutamate dehydrogenase 1, mitochondrial |
| Species: | Rat |
| Sample type: | serum, plasma, tissue homogenates or other biological fluids. |
| Experimental method: | Sandwich |
| Shelf life: | 12 months |
| Gene ID: | 24399 |
| UniProt ID: | P10860 |
| Component: | 1. Pre-coated, ready to use 96-well strip plate 1 2. Plate sealer for 96 wells 2 3. Standard 2 4. Diluents buffer: 1×45 mL 5. Detection Reagent A: 1×120 μL 6. Detection Reagent B: 1×120 μL 7. TMB Substrate: 1×9 mL 8. Stop Solution: 1×6 mL 9. Wash Buffer (30× concentrate): 1×20 mL |
Background
Enables enzyme binding activity and glutamate dehydrogenase (NAD+) activity. Involved in cerebellum development; long-term memory; and response to aluminum ion. Predicted to be located in endoplasmic reticulum and mitochondrial matrix. Predicted to be active in mitochondrion. Biomarker of brain ischemia; childhood absence epilepsy; fascioliasis; hepatic encephalopathy; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; and hypoglycemia. Orthologous to several human genes including GLUD1 (glutamate dehydrogenase 1).
