tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
25700
UniProt ID:
P35559
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables NF-kappaB binding activity and protease binding activity. Involved in several processes, including negative regulation of release of cytochrome c from mitochondria; negative regulation of vasoconstriction; and positive regulation of T cell mediated cytotoxicity. Located in apical plasma membrane; basolateral plasma membrane; and membrane raft. Part of protein-containing complex. Biomarker of graft-versus-host disease. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; obesity; toxic shock syndrome; type 2 diabetes mellitus; and urinary tract infection. Orthologous to human HSPA1B (heat shock protein family A (Hsp70) member 1B).
