MKI67; KIA; Ki-67; Antigen Identified By Monoclonal Antibody Ki-67
Species:
Rat
Sample type:
tissue homogenates, cell lysates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
291234
UniProt ID:
D4A0Y6
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Predicted to enable growth hormone receptor binding activity; non-membrane spanning protein tyrosine kinase activity; and protein phosphatase binding activity. Involved in several processes, including positive regulation of activated T cell proliferation; positive regulation of calcium ion transport; and positive regulation of nitric oxide biosynthetic process. Predicted to be located in several cellular components, including cytoplasm; cytoskeleton; and endomembrane system. Predicted to be active in cytosol. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Used to study graft-versus-host disease. Biomarker of tongue squamous cell carcinoma. Human ortholog(s) of this gene implicated in hematologic cancer (multiple) and severe combined immunodeficiency. Orthologous to human JAK3 (Janus kinase 3).
