serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
298296
UniProt ID:
P59996
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Enables endopeptidase activity. Involved in several processes, including nervous system development; protein processing; and response to interleukin-1. Located in several cellular components, including perikaryon; perinuclear region of cytoplasm; and trans-Golgi network. Used to study hyperglycemia and type 2 diabetes mellitus. Biomarker of glucose metabolism disease (multiple); hyperthyroidism; hypothyroidism; islet cell tumor; and visual epilepsy. Human ortholog(s) of this gene implicated in obesity and proprotein convertase 1/3 deficiency. Orthologous to human PCSK1 (proprotein convertase subtilisin/kexin type 1).
