BSP1; JV4-1; JV41; MADH1; MADR1; SMAD Family Member 1; Mad-related protein 1; Transforming growth factor-beta-signaling protein 1; Mothers against DPP homolog 1
Species:
Rat
Sample type:
tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
25671
UniProt ID:
P97588
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Predicted to enable several functions, including SMAD binding activity; enzyme binding activity; and nucleic acid binding activity. Involved in several processes, including BMP signaling pathway; cardiac muscle hypertrophy in response to stress; and positive regulation of dendrite morphogenesis. Predicted to be located in cytoplasm and nuclear inner membrane. Predicted to be part of heteromeric SMAD protein complex and homomeric SMAD protein complex. Predicted to be active in chromatin and male germ cell nucleus. Used to study pulmonary hypertension. Biomarker of glomerulonephritis; male infertility; nephrotic syndrome; and pulmonary hypertension. Orthologous to human SMAD1 (SMAD family member 1).
