SNC-A; aSYN; PD1; PARK1; PARK4; NACP; Non-A Beta Component Of Alzheimers Disease Amyloid Precursor Protein; Non-A4 component of amyloid precursor
Species:
Rat
Sample type:
serum, plasma, tissue homogenates or other biological fluids.
Experimental method:
Sandwich
Shelf life:
12 months
Gene ID:
29219
UniProt ID:
P37377
Components:
1. Pre-coated, ready to use 96-well strip plate 1
2. Plate sealer for 96 wells 2
3. Standard 2
4. Diluents buffer: 1×45 mL
5. Detection Reagent A: 1×120 μL
6. Detection Reagent B: 1×120 μL
7. TMB Substrate: 1×9 mL
8. Stop Solution: 1×6 mL
9. Wash Buffer (30× concentrate): 1×20 mL
Background
Predicted to enable several functions, including cholesterol-protein transferase activity; laminin-1 binding activity; and metal ion binding activity. Involved in several processes, including nervous system development; positive regulation of cell differentiation; and reproductive structure development. Acts upstream of or within ventral spinal cord interneuron specification. Located in several cellular components, including dendrite; neuronal cell body; and synaptic vesicle. Is active in several cellular components, including glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and postsynapse. Used to study Parkinsonism and myocardial infarction. Biomarker of several diseases, including VACTERL association; chronic kidney disease; esophageal atresia/tracheoesophageal fistula; ocular hypertension; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; holoprosencephaly (multiple); hypoplastic or aplastic tibia with polydactyly; middle cerebral artery infarction; and polydactyly (multiple). Orthologous to human SHH (sonic hedgehog signaling molecule).
